Miami to Key West: 3 Day Road Trip Itinerary
20 Beautiful Road Trips to Plan NextFlorida, USA
A three-day ocean drive along the Overseas Highway, with Key Largo and Islamorada stops before Key West. This itinerary is one-way.

Suggested season: December–April
Driving estimates exclude stops, traffic and ferry waits. Pins represent town/area centres; use the daily map links for navigation.
Day 1: Miami → Key Largo → Islamorada
Stop in Key Largo for the waterfront or a reef trip in suitable weather. Watch sunset and stay overnight in Islamorada.
2–3 hours driving · Overnight: Islamorada
Google MapsDay 2: Islamorada → Marathon → Key West
Break the drive in Marathon and cross Seven Mile Bridge. Park on arrival in Key West and explore the old town on foot.
2–3 hours driving · Overnight: Key West
Google MapsDay 3: Key West
Choose Hemingway Home or a sea activity, then relax by the coast. Dry Tortugas needs a separate, prebooked full day.
0–1 hours driving · Overnight: End of itinerary
Google MapsBefore you drive
The return to Miami is not included. Check one-way rental fees and storm alerts; boat trips depend on weather.
Official destination informationEstimated budget for two
Illustrative October 2026 planning allowances, not live prices or quotes. Two adults, one rental car, a shared mid-range room and 2 nights. Flights, visas, insurance upgrades, deposits and one-way rental fees excluded. Peak season and major activities may exceed these amounts.
- Room per night: 180–320 USD
- Car per day: 60–110 USD
- Food for two per day: 70–120 USD
- Fuel for the trip: 50–90 USD
- Visits, parking and toll allowance: 100–240 USD
Total range including 10% reserve: 990–1826 USD
Midpoint estimate / per person: 1408 / 704 USD
Hours, fees and access may change; check official links before travelling.